The use of Depo-Provera for these women may be particularly concerning.ĭepo-Provera can be an effective medication for birth control and reducing symptoms associated with having periods. In some autoimmune situations, increased (abnormal) blood clotting is a problem. ![]() People with DS are thought to have a higher incidence of autoimmune conditions such as autoimmune thyroid disease, Rheumatoid arthritis, and others. This seems to be on the basis of autoimmune conditions (the body's immune system being directed at a component of the body). We have found a number of our patients with a predisposition to abnormal clotting. We may reduce cyclic mood changes but increase overall depression or mood problems.ĭepo-Provera can increase the risk of abnormal blood clotting. We have found this to be a problem, for example, in a woman we are trying to reduce mood swings associated with the menstrual cycle. Particularly in the first year of use, the periods (or spotting/bleeding) may be less predictable and more frequent and this can reduce the benefit of trying to reduce the periods (at least in the first year).ĭepo-Provera can contribute to mood changes or depression. There are some particular issues that we consider for our female patients with Down syndrome such as:ĭepo-Provera does require an injection every 3 months which some of our patients find challenging.ĭepo-Provera can increase osteoporosis (thinning of the bones) which is already more common in people with DS. (Pfizer, the manufacturer of the drug, produced a handout that you can find at this link. It doesn't protect against sexually transmitted diseases. Since periods often are stopped altogether while using Depo-Provera, it can be helpful for those women who are challenged by managing their periods (which can be an issue for some women with Down syndrome). It is an effective form of birth control and, when it eliminates periods completely, it can be an effective way to eliminate symptoms associated with periods. Many women will stop having their menses (periods) when receiving the Depo-Provera injection regularly (menses will resume when the shot is no longer used). Reduce periods and/or symptoms from periods We received a question about the use of Depo-Provera.ĭepo-Provera is an injection of progesterone that is used to:
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There are also some interesting innovations under the hood, including the ability to play online streams and YouTube playlists via IINA, as well as all your local files. It supports everything from the MacBook Pro Touch Bar to trackpad gestures for controls. IINA embraces the latest features of MacOS, including an interface theme designed for Dark Mode and picture-in-picture compatibility for watching video playback while working on other things. Elmedia supports Apple Silicon natively and is updated regularly.ĭownload Elmedia Video Player from the App store. There’s plenty of focus on video as well, so it also works as an alternative movie player. File support is also strong, with compatible formats including M4A, WMA, MP3, M4V, and dozens more. ![]() Playlists are easy to create and sort through, and controls are very intuitive: We especially like the common-sense broadcast button that allows you to quickly link to any connected device, such as speakers, Apple TV, or a smart TV for various audio options. This MacOS media player has an incredibly smooth, stylish interface that offers something very different from Apple Music while still looking like a part of your Mac. And if you’re primarily interested in mobile music players, we’ve got some killer iOS apps for you to check out too. More interested in streaming music instead? Take a look at our side-by-side comparison of Spotify and Apple Music to see how these services stack up. Whether you’re an audiophile with a thirst for feature-heavy players or a casual listener looking for a no-frills option, we’re sure you’ll find something here that suits you. ![]() ![]() If you’ve been looking for a cost-free alternative to Apple Music, there are plenty of great apps out there to check out. There are multiple apps out there you can use to manage your music library if you’re on a Mac, but you may have trouble deciding which is best for you. ![]() ![]() It is one of the easiest and user-friendly soundboard apps for Discord and compatible with other programs like Skype and TeamSpeak.Īnother fantastic feature of VoiceMod is that its gallery updates new sounds and effects every month, which is another reason users admire the software. It converts your voice into different ones, like robotic, satanic, normal male or female voices. More about Voicemod is that it is a voice modifier. Indeed, one unique Soundboard for Discord is VoiceMod that comes with several sound effects to escalate your fun and convenience. Voicemod does not discriminate between a gamer and a streamer, and it allows you to have your favorite sounds. Besides, you can search for different sounds in the instant search bar and make a list of different sounds for your convenience. You can also play sounds for yourself only on headphones that most gamers prefer. It also allows you to block your microphone if need be. It is both a sound recorder and an editor. It lets you play sounds on the microphone and gives you a speechless sound to speakers and microphone experience. Therefore, its amazing functionality does not let it remain just an ‘ordinary’ media player. We can say that Soundpad is an ordinary media player that works wonders for Discord users. Here are the top 13 best soundboards for Discord: 1. Please don’t worry if you haven’t found the best soundboard for Discord since we have your back! This article contains a list of the best soundboard for Discord that are highly compatible with the app. In conclusion Top 13 best soundboards for Discord ![]() ![]() ![]() Her approach is as eclectic as it is kinetic: new single Pressure is caramel-smooth pop older number Big Racks merges extremely wonky synth bass with taut drums that nod to old-school funk and hyperpop, while the beat-heavy hip-hop of ATM features the kind of sharp hooks and joyous bounce that recall the heyday of Missy Elliott (who guests on the recorded version). I honestly cannot wait for her next concert and song releases.Growing up in a Hackney household soundtracked by her father’s Ghanian highlife music and her mum’s heavy rotation of MTV icons such as Kelis and Lil’ Kim has clearly rubbed off on Runway. However, this concert has left me with s uch fun and exhilarating memories of the awe-inspiring, Michelle Obama – approved artist who is only just starting her journey. I was quite sad that the concert ended after this song as myself and many other people were left desperately wanting more. Her devotion clear ly touched Bree so much that she allowed her to perform the encore with her. The final song s h e performed was HOT HOT – so popular that it received an encore where she bought a fan on stage who ’d travelled all the way from Dublin to Birmingham to attend the concert having not wanted to reschedule it again. We were even gifted with an amazing guitar solo from one of her band members. Being on e of the more romantic songs in her discography it s eemed a fitting choice to start the closing of the concert almost like a love letter to her fans that she cares about so dearly. ROLLS ROYCE was the next song before leading into the penultimate song All Night. Continuing the set list, she performed another one of her biggest hit’s ATM, however a whole acapella version of the first verse and chorus was performed by the entire venue initially, after Bree prompted us with four simple words “Do you like money?”. We are greatly anticipating its official release. This was a very heartfelt pop ballad which had all of us in the crowd swaying our arms from side to side under the mellow blue lights. Next, she decided to debut a brand-new unreleased single called Somebody Like You. She then moved on to sing a few of my favourites Big Racks and GUCCI. As well as a very talented singer, rapper and musician she’s proven to be a n amazing dancer as her stage presence held us in ti ght grip whilst dancing with her crew. The popstar seemed hugely impressed with the energy levels from the start and how full the venue was, stating that we were livelier than the previous concert in Manchester !Īfter the short intermission she moved onto to perform her latest single Pressure. On stage, Bree made an effort to interact with the crowd in a light and cheerful way, curio u s to know what a genuine Birmingham accent sounded like as she stated it was her first time in the city, she consulted some (very lucky!) members of the audience with great humour. Sh e kicked off the concert with her powerful headbangers A PES ** T and L ITTLE N OKIA from her mixtape which kept the energy levels high, whilst e veryone in the crowd was chanting all the lyrics as if they had written the song s themselves. Prior to her arrival the crowd had been chanting “BREE! BREE! BREE!” in anticipation – a sure sign of an already excitable fanbase. Īs soon as the band came on the stage and played the beginning r iffs of the first song, screams erupted from the audience and crescendoed as Bree stepped onto the stage in a striking red outfit. A fter the immense success of her debut mixtape 2000AND 4EVA her latest singles HOT HOT and Pressure. This is the BET Award winner ’ s first tour which spans across Manchester, Birmingham and London. I must say we definitely g a ve the up-and-coming superstar the energetic crowds that she deserves. Bree Runway had reached the halfway point of her debut tour in Birmingham last Friday () on the top floor of the O2 In s titute. If user use that type text in any type illegal activity, only user is the responsible for his action. ![]() Warnings: This warning for every new or old the dark web links explorer, we are writing “red text” here that are directly or indirectly not related to any deep web or Tor network site. If all things are done, now you are ready to explore the dark web links. 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VPM incorporates four additional large diameter payload tubes in a new hull section located amidships. The next major change is the incorporation of the Virginia Payload Module (VPM), starting with the second Block V ship, SSN 803, currently under construction. Block III hulls include the eight ships procured from 2008 through and 2013 (SSNs 784-791). The Block III design changes will continue on all future Virginias and were successfully proven out during USS North Dakota's (SSN 784) builder sea trials in August 2014. The VPTs simplify construction, reduce acquisition costs, and provide for more payload flexibility than the smaller VLS tubes due to their added volume. The new bow also replaces the 12 individual Vertical Launch System (VLS) tubes with two large diameter 87-inch Virginia Payload Tubes (VPTs), each capable of launching six Tomahawk cruise missiles using Multiple All-up Round Canisters (MACs) already employed on SSGNs. Most of the changes are found in the bow where the traditional, air-backed sonar sphere has been replaced with a water-backed Large Aperture Bow (LAB) array which reduces acquisition and life-cycle costs while providing enhanced passive detection capabilities. Additionally, through the extensive use of modular construction, open architecture, and commercial off-the-shelf components, the Virginia class is designed to remain state-of-the-practice for its entire operational life through the rapid introduction of new systems and payloads.Īs part of the Virginia-class' third, or Block III, contract, the Navy redesigned approximately 20 percent of the ship to reduce their acquisition costs. With the removal of the barrel periscopes, the ship's control room has been moved down one deck and away from the hull's curvature, affording it more room and an improved layout that provides the commanding officer with enhanced situational awareness. ![]() In Virginia-class SSNs, traditional periscopes have been supplanted by two photonics masts that host visible and infrared digital cameras atop telescoping arms. The class also has a large lockout truck (LOT) for divers. The class has special features to support SOF, including a reconfigurable torpedo room which can accommodate a large number of SOF personnel and all their equipment for prolonged deployments, as well as future off-board payloads. The Virginia class has several innovations that significantly enhance its warfighting capabilities, including in littoral - or coastal - operations. Twenty-oneVirginias have been commissioned to date, and they will replace Los Angeles Class submarines as they retire. The Navy continues to build the next-generation attack submarine, the Virginia (SSN 774) class. This hull section provides for additional payloads to accommodate advanced technology used to carry out classified research and development and for enhanced warfighting capabilities. The third ship of the class, USS Jimmy Carter (SSN 23), has a 100-foot hull extension called the multi-mission platform. Though lacking VLS, the Seawolf class has eight torpedo tubes and can hold up to 50 weapons in its torpedo room. Commissioned July 19, 1997, USS Seawolf-class (SSN 21) submarines are exceptionally quiet, fast, well-armed, and equipped with advanced sensors. The Navy also has three Seawolf-class submarines. Thirty of those are equipped with twelve Vertical Launch System (VLS) tubes for firing Tomahawk cruise missiles. Los Angeles-class (SSN 688) submarines are the backbone of the submarine force, with approximately forty now in commission. The Navy has three classes of SSNs in service. 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After every scan, it notified me that my PC was getting slower and attempted to get me to try out or purchase Avast Cleanup Premium to “resolve the issue.” That said, Avast’s malware scanner constantly tries to upsell you, which I found quite annoying. It was also able to catch the samples when they were zipped and encrypted. When I turned it on and attempted to download the malware samples I had previously used for testing, it prevented all of the downloads. Create your own scans to suit your needs.Īvast’s real-time protection is very good as well. Scans specific files or folders direct from your desktop. Scans files before your operating system is fully loaded. Scans specific folders or drives (including external drives). Scans areas on your device where malware is usually found. ![]() This allows you to target specific areas where you suspect there might be a problem in order to save time. I like the large number of scan options Avast provides. 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Its free plans, Avast Free Antivirus and Avast One Essentials, include the core security features you need to protect your devices. It also provides strong web protection, a Rescue Disk, a secure browser, advanced anti-tracking protection, and a set of decent system optimization tools.Īvast has free and premium plans for Windows, Mac, Android, and iOS. It scored a 100% malware detection rate during my tests. RISK-FREE FOR 30-DAYS - TRY AVAST NOW Avast Antivirus Full ReviewĪvast provides great security, includes a ton of extra features, and is very user-friendly. All of its plans come with a 30-day money-back guarantee, so you can try it out risk-free. It provides excellent malware protection, is super easy to use, and has lots of extra features. Overall though, Avast is still one of the better antivirus software programs. Its VPN is pretty mediocre too - it has middling speeds, it keeps connection logs, and its server coverage isn’t great. And while Norton and other top brands include password managers and parental controls, Avast doesn’t have either of these features. For example, its data breach monitoring is pretty limited - top antiviruses like Norton are able to scan for many more types of personally identifiable information. However, while Avast is a very good antivirus, there are areas where it could improve. The premium plans Avast offers have a wide range of extras, including: Its web protections are very good as well, performing significantly better than the default protections of Chrome, Firefox, and Edge. 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And somewhere inside it is the information that could help him-in fact it may even save his life.Īnother example of high concept literary fiction costuming itself in the tropes, set designs and jargon of genre fiction, while striving to create something unique, penetrating and memorable.Īnd, in this case, succeeding brilliantly. It’s called How to Live Safely in a Science Fictional Universe, and he’s the author. He learns that the key may be found in a book he got from his future self. Accompanied by TAMMY, an operating system with low self-esteem, and Ed, a nonexistent but ontologically valid dog, Yu sets out, and back, and beyond, in order to find the one day where he and his father can meet in memory. When he’s not taking client calls or consoling his boss, Phil, who could really use an upgrade, Yu visits his mother (stuck in a one-hour cycle of time, she makes dinner over and over and over) and searches for his father, who invented time travel and then vanished. That’s where Charles Yu, time travel technician-part counselor, part gadget repair man-steps in. Every day, people get into time machines and try to do the one thing they should never do: change the past. Minor Universe 31 is a vast story-space on the outskirts of fiction, where paradox fluctuates like the stock market, lonely sexbots beckon failed protagonists, and time travel is serious business. ![]() A story of a son searching for his father. ![]() Gold is available commercially with a purity of 99.999+%. A mixture of one part nitric acid with three of hydrochloric acid is called aqua regia (because it dissolved gold, the King of Metals). Disodium aurothiomalate is administered intramuscularly as a treatment for arthritis. Gold has 18 isotopes 198Au, with a half-life of 2.7 days, is used for treating cancer and other diseases. The most common gold compounds are auric chloride and chlorauric acid, the latter being used in photography for toning the silver image. It is used for coating certain space satellites, as it is a good reflector of infrared and is inert. It is also extensively used for jewelry, decoration, dental work, and for plating. It is used in coinage and is a standard for monetary systems in many countries. It is a good conductor of heat and electricity, and is unaffected by air and most reagents. It is a soft metal and is usually alloyed to give it more strength. It is the most malleable and ductile metal 1 oz. The Purple of Cassius is a delicate test for auric gold. It is metallic, having a yellow color when in a mass, but when finely divided it may be black, ruby, or purple. Of all the elements, gold in its pure state is undoubtedly the most beautiful. It is estimated that all the gold in the world, so far refined, could be placed in a single cube 60 ft. As yet, no method has been found for recovering gold from sea water profitably. Gold occurs in sea water to the extent of 0.1 to 2 mg/ton, depending on the location where the sample is taken. Refining is also frequently done by electrolysis. The metal is recovered from its ores by cyaniding, amalgamating, and smelting processes. production comes from South Dakota and Nevada. About two thirds of the world's gold output comes from South Africa, and about two thirds of the total U.S. It occurs in veins and alluvial deposits, and is often separated from rocks and other minerals by mining and panning operations. Known and highly valued from earliest times, gold is found in nature as the free metal and in tellurides it is very widely distributed and is almost always associated with quartz or pyrite. When an organism dies, it stops taking in carbon-14, so the ratio of carbon-14 to carbon-12 in its remains, such as fossilized bones, will decline as carbon-14 decays gradually to nitrogen-14 2 ^2 2 squared. As animals eat the plants, or eat other animals that ate plants, the concentrations of carbon-14 in their bodies will also match the atmospheric concentration. As plants pull carbon dioxide from the air to make sugars, the relative amount of carbon-14 in their tissues will be equal to the concentration of carbon-14 in the atmosphere. ![]() These forms of carbon are found in the atmosphere in relatively constant proportions, with carbon-12 as the major form at about 99%, carbon-13 as a minor form at about 1%, and carbon-14 present only in tiny amounts 1 ^1 1 start superscript, 1, end superscript. For example, carbon is normally present in the atmosphere in the form of gases like carbon dioxide, and it exists in three isotopic forms: carbon-12 and carbon-13, which are stable, and carbon-14, which is radioactive. |
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